The Retroconversion of Immature Mediastinal Teratoma with Chemothearpy : A Case Report

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The Retroconversion of Immature Mediastinal Teratoma with Chemothearpy : A Case Report

Md. Tajul Islam1, Md. Kamrul Alam2, Md. Osman Goni3, Md. Serajus Salekin4, Md. Mehedi Hasah5,Abdul Monim Sarker 6, Newab Wahed ,Tanvir Rahman8,Hossain Al Mahmood9 ,Md. Mohsin Reza10

Abstract: Mediastinum is a common localization of extra gonadal teratoma. Mediastinal teratoma is an infrequent germ cell tumor,comprising of 1 to 5 % of all mediastinal tumors. Immature mediastinal teratoma are rare malignant neoplasm that can metastasize and recure, are characterized by present of various tissue that histologically resemble embryonal structures. Mediastinal immature teratoma and there association with chemotherapeutic retroconversion have been reported few in the literature, the retroconversion of mediastinal teratoma into mature teratoma is quite uncommon. A 18 years old boy was diagnosed a case of immature mediastinal teratoma by Computed Tomography guided FNA (Fine Needle Aspiration ) and received 6 cycles chemotherapy by Bleomycin etoposide and cisplatin regimen , after that surgically total excision of tumor was done and histopathological report reveals mature teratoma which is presented in this paper.

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